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Some hair, but this effect is usually temporary. Although Synthroid will speed up your metabolism, it is important to take it regularly at the same time every day. Most commonly prescribed of all the thyroid supplements. Synthroid can also reduce the effects of digitalis glycosides, which might require an increase in dosage. Synthroid should be used with caution, when taking Synthroid. Synthroid may rapidly swell and disintegrate resulting in choking, gagging, the tablet getting stuck in your throat, or difficulty swallowing.