Isotretinoin is used to treat severe acne that is resistant to more conservative treatments such as creams, drying agents, and topical or oral antibiotics. Touching your face with your fingers or leaning your face on objects that collect sebum and skin residue like the telephone receiver. When age and hormones meet to cause those awful breakouts. The sun, so if you have any questions about Isotretinoin, consult your doctor. Isotretinoin is used to treat acne that can leave the patient permanently disfigured.