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Metformin may be used with lifestyle changes such as diet and exercise program to control high blood sugar in people with type 2 diabetes the pancreas does not produce sufficient insulin and the cells of the body are resistant to the low levels of insulin circulating in the blood. Glucophage tablets contain the active ingredient Metformin hydrochloride. Metformin can be used in combination with other anti-diabetic medicines to provide better control of blood sugar. Use this medication regularly in order to get the most benefit from it.