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Dominic wrote: "Nolvadex works by binding to the estrogen receptors in the body, preventing estrogen from binding to these sites. Nolvadex, is the trade name for the drug Tamoxifen may not only help to treat women with breast cancer, it might also help them to conceive. Bodybuilders who take Nolvadex also use anabolic steroids at the same time. Tamoxifen citrate works by competitively binding to target estrogen sites like those at the breast. The ability of Tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. Nolvadex is certainly the most popular anti-estrogen among steroid users by far. Women should remember to be very cautious when considering the use of Nolvadex, as they are usually very sensitive to changes in the activity of estrogen. With the Tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved."