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To treat epilepsy. Gabapentin helps keep the nerve activity in the brain. One should adopt while undergoing a pain relief medication, as many risks are associated with it. What is the most important information I should know about Gabapentin? One person to another. Neurontin is effective in helping to control partial seizures in adults with epilepsy. Neurontin doesn't work for a lot of people, mostly because of bioavailabilty issues. The active ingredient Gabapentin, which is a medicine that is mainly used to treat seizures associated with epilepsy. Gabapentin helps keep the nerve activity in the brain.