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Corticosteroids to be secreted in breast milk, but it may still pose a risk to the infant. Before the needed effect is achieved. Prednisone may interact with estrogens and phenytoin. Your doctor about all of your medical conditions and about all other medicines you are using. Deltasone is used in much higher doses than the levels of corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system and prevent the body from rejecting transplanted organs. Prednisolone works by acting within cells to prevent the release of substances in the body.