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Emma Carpenter said: "Lexapro blocks the re-absorption of serotonin by the first nerve cell. There have been some complaints about it, like its alleged contributions to weight gain and its high price. Lexapro blocks the re-absorption of serotonin by the first nerve cell. Lexapro works by increasing the amount of serotonin, a chemical messenger in the brain that helps maintain mental balance. This medicine is a selective serotonin reuptake inhibitor. Escitalopram helps to restore the brain's chemical balance by increasing the available supply of serotonin, a natural substance in the brain believed to influence mood."